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Location:  This position may be performed remotely but requires flexibility and a willingness to travel as needed.   Position Summary   Praxis is seeking a strategic, highly collaborative Senior Product Manager to help shape and execute commercialization strategy for our growing portfolio of therapies focused on central nervous system disorders. This role sits at the intersection of science, customer insight, and business strategy, helping translate complex clinical innovation into meaningful impact for patients, caregivers, and healthcare providers.   This is a high-ownership role for someone who thrives in ambiguity, moves with urgency, and knows how to align teams around clear priorities and outcomes. You will lead cross-functional initiatives spanning product strategy, launch readiness, market development, messaging, customer engagement, and competitive positioning. You will be expected to think beyond tactical execution — identifying opportunities, challenging assumptions, and helping shape commercial direction in a fast-moving biotech environment.   The right person combines strategic thinking with operational excellence. You are intellectually curious, action-oriented, and trusted by cross-functional partners because you bring clarity, accountability, and sound judgment. Most importantly, you are motivated by the opportunity to help deliver transformative therapies to patients with significant unmet needs.   Primary Responsibilities   Lead development and execution of integrated product and commercialization strategies aligned to corporate and portfolio objectives    Drive cross-functional alignment across Commercial, Medical Affairs, Market Access, Regulatory, Clinical, and Corporate Communications teams to support launch readiness and ongoing product strategy    Translate scientific and clinical data into differentiated product positioning, messaging, and customer engagement strategies    Partner with market research and analytics teams to generate actionable insights from customer feedback, market dynamics, competitive intelligence, and performance metrics    Lead development of disease education, promotional, and non-promotional initiatives in partnership with agency and internal stakeholders    Identify strategic risks, gaps, and opportunities proactively, helping teams make informed business tradeoff decisions    Manage complex initiatives across multiple stakeholders while ensuring speed, quality, accountability, and compliance    Contribute to long-range planning, portfolio strategy discussions, and commercialization readiness activities    Serve as a collaborative leader and trusted thought partner who elevates cross-functional execution and organizational effectiveness      Qualifications and Key Success Factors   Bachelor’s degree required; advanced degree preferred    Demonstrated experience leading product strategy, commercialization, brand management, or launch initiatives within biotech, pharmaceutical, or healthcare environments    Strong ability to synthesize scientific, customer, and market insights into clear strategic direction and actionable plans    Experience influencing cross-functional stakeholders and driving alignment in complex, matrixed environments    Excellent strategic thinking, communication, and presentation skills    Strong project leadership and organizational skills with ability to manage multiple priorities simultaneously    Comfortable operating in fast-paced, evolving organizations with high accountability and autonomy    Demonstrated ability to navigate ambiguity, challenge assumptions constructively, and drive result